Effects of Lippia sidoides essential oil, thymol, p-cymene, myrcene and caryophyllene on rat sciatic nerve excitability

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Effects of Lippia sidoides essential oil, thymol, p-cymene, myrcene and caryophyllene on rat sciatic nerve excitability

Lippia sidoides Cham is a typical herb species of Northeast Brazil with widespread use in folk medicine. The major constituents of the essential oil of L. sidoides (EOLs) are thymol, p-cymene, myrcene, and caryophyllene. Several studies have shown that the EOLs and its constituents have pharmacological effects, including antibacterial, anti-inflammatory, antioxidant and neuroprotective activity...

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Antimicrobial activity of the essential oil from Lippia sidoides, carvacrol and thymol against oral pathogens.

Dental caries and periodontal disease are associated with oral pathogens. Several plant derivatives have been evaluated with respect to their antimicrobial effects against such pathogenic microorganisms. Lippia sidoides Cham (Verbenaceae), popularly known as "Alecrim-pimenta" is a typical shrub commonly found in the Northeast of Brazil. Many plant species belonging to the genus Lippia yield ver...

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Structurally Related Monoterpenes p-Cymene, Carvacrol and Thymol Isolated from Essential Oil from Leaves of Lippia sidoides Cham. (Verbenaceae) Protect Mice against Elastase-Induced Emphysema.

BACKGROUND Chronic obstructive pulmonary disease (COPD) is characterized by irreversible airflow obstruction and inflammation. Natural products, such as monoterpenes, displayed anti-inflammatory and anti-oxidant activities and can be used as a source of new compounds to COPD treatment. Our aim was to evaluate, in an elastase-induced pulmonary emphysema in mice, the effects of and underlying mec...

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Lippia sidoides Essential Oil Encapsulation by Angico Gum/Chitosan Nanoparticles

Nanoparticulas de quitosana (CH) e goma do angico (AG), dopadas com óleo essencial de Lippia sidoides (Ls) foram preparadas e caracterizadas em relação às suas composições, distribuição de tamanho de partículas, estabilidade térmica, bem como as liberações in vitro e in vivo. Os dados obtidos revelaram que as nanopartículas preparadas usando razões Ls:AG variando de 1:2 a 1:20, apresentaram dop...

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Essential Oil of Ocimum basilicum L. and (−)-Linalool Blocks the Excitability of Rat Sciatic Nerve

The racemate linalool and its levogyrus enantiomer [(-)-LIN] are present in many essential oils and possess several pharmacological activities, such as antinociceptive and anti-inflammatory. In this work, the effects of essential oil obtained from the cultivation of the Ocimum basilicum L. (EOOb) derived from Germplasm Bank rich in (-)-LIN content in the excitability of peripheral nervous syste...

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ژورنال

عنوان ژورنال: Brazilian Journal of Medical and Biological Research

سال: 2017

ISSN: 1414-431X,0100-879X

DOI: 10.1590/1414-431x20176351